Study of disintegrant from natural product

Abstract

Disintegrants are the excipients used in tablets to enhance disintegration. Natural disintegrants are used for their non-toxic behavior. Flaxseed is seed obtained from Linum Usitatissimum (Family Linaceae) and rich in polysacchride. As per literature the mucilage obtained was found promising to promote disintegrant as a tableting excipient. Extraction of the mucilage from the seed needs to be done in simple and economic way. The extraction and addition of mucilage intragranularly served the purpose of disintegrant. The extracted mucilage should be free from carbohydrate and protein. The present study showed the extracted mucilage as disintegrant and its comparison with starch. Key words: Disintegrant, Mucilage, Extraction