Abstract:
TRZ (trazodone hydrochloride) is a well-known antidepressant that belongs to the competitive
serotonin reuptake inhibitors class of drugs (SARI). This drug is recommended for the
treatment of depression. It may help to enhance your demeanor, appetite, and energy level, and
also reduce depression-related anxiety and sleeplessness. Trazodone comes as 25 mg, 50 mg,
100 mg, 150 mg, & 300 mg tabs for oral use. There is also a 150 mg & 300 mg extended release
version available as tablets. According to the extant literature studies, multiple analytical
methods for estimating trazodone hydrochloride alone and in combination with other
antidepressants are available. For estimating trazodone hydrochloride, many analytical
methods such as RP-HPLC, UV, and Spectrophotometric methods are available. There is a
need to establish an assay technique for estimating trazodone dosage form since the existing
literature report does not include any methodical assay method for component quantification
that reflects the accurate purity feature of sample to produce average accurate findings.
